The Deeper Genome, John Parrington

I should have reviewed this when I read it, but it seems to have gotten lost in the shuffle somewhere. I’m left with only general impressions and the knowledge that I intended to give it a four star rating. That alone should tell you it’s decent pop-science, delving into the genome and trying to give the reader a deeper understanding of it — not just the basic string of AACTGGA or whatever, but more detail. The first chapters are more basic, of course, giving the reader a bit of a background against which to evaluate all the new research.

I recall it being clear and easy to read, and where it went into epigenetics, microRNAs and piRNAs, I was fascinated. Some of this stuff, it only touches on, because it’s complex or not fully researched yet. Still a good read!

Rating: 4/5

One Renegade Cell, Robert Weinberg

One Renegade Cell is a classic by now in terms of pop science books which explain cancer for an interested but non-specialist audience. It’s a little out of date, and some of the hopes Weinberg talks about in terms of treatments to come haven’t come to pass at all. But the basics are still true, and you can get a good basic understanding of how cancer works by reading it. It’s clear and accessible, and I didn’t find it prone to fear-mongoring either — sometimes when someone is writing about cancer, it seems like they can’t help but try to scare the reader silly.

One Renegade Cell doesn’t try to mystify cancer or play up its impact; the impact of cancer pretty much speaks for itself. It’s a solid read, even though it’s out of date now.

Rating: 3/5

The Making of the Fittest, Sean B. Carroll

The Making of the Fittest is really about that subtitle: “DNA and the ultimate forensic record of evolution”. It’s all about showing that DNA holds the record of evolution, and essentially proves what is difficult to see in real time. There are some good examples, but overall I found myself wondering if anyone who wasn’t already convinced would become convinced by this book. DNA isn’t exactly a secret, and the fact that many species share DNA isn’t either, and yet people still doubt that that means anything.

It’s a good enough read if you’re looking for examples, though, and good if you really want to get to grips with examples of convergent evolution, too.

Rating: 3/5

Why Dinosaurs Matter, Kenneth Lacovara

Received to review via Netgalley; publication date 19th September 2017

The idea of this book is pretty much encapsulated in the words from the summary: “What can long-dead dinosaurs teach us about our future? Plenty.” It’s the story of the dinosaurs as a highly successfully set of creatures who ruled the world — for a time. It’s also the story of their decline and fall, so to speak, and the lessons we can learn from them. Also, a reminder that a penguin is very literally a dinosaur, just as we’re very literally primates.

There’s nothing revelatory here if you’re into dinosaurs, but if you’re looking for something more general than David Hone’s The Tyrannosaur Chronicles, something to get you up to date on current dinosaur scholarship, this isn’t a bad place to start. And I agree with Lacovara: dinosaurs shouldn’t be viewed as synonymous with something obsolete. They ruled the world for a reason.

Rating: 3/5

The Trouble With Physics, Lee Smolin

I came out of reading this book with a pleasing illusion that I understood something of the state of modern physics. Smolin’s style worked for me in explaining things well enough that, for once, I wasn’t left boggling and having to reread pages over and over again to cram the concepts into my head. Perhaps it helps that he’s not an inveterate supporter of string theory, and can explain where it doesn’t work as an explanation for our universe and why — sometimes, it helps to know where concepts break down as much as it helps to know where they succeed.

Part of the book isn’t just about physics at all, though: it’s about the progress of science in general, and how science progresses. I’m not sure Smolin really gets at anything profound here, but when it comes to the specifics of critiquing why physics has come to a standstill, he genuinely cares and genuinely wants to solve the issue. The way he presents it, it’s clear that it’s time for people to re-evaluate string theory and accept that quite possibly it will never yield the answers we’re looking for.

Some days after reading it, being me, I can no longer explain string theory to anyone else, but I can explain why it doesn’t work, so I got something out of this! And I more or less enjoyed letting it turn my brain inside out, too.

Rating: 4/5

15 Million Degrees, Professor Lucie Green

If you want to know all the things we know or guess about the sun, this is definitely the book for you. Lucie Green isn’t just a science communicator — she’s actually doing the research, so she knows what the current questions are, what the latest research is, and all the history of how we came to know what we know. Her enthusiasm is plain throughout, and she does a good job of describing both the actual physical events of the sun, and the sensation of observing and understanding them.

If you’re not hugely into physics, you might find that a few chapters do start to drag. But for the most part, it’s a fascinating book — and there’s a lot of stuff I didn’t know.

Rating: 3/5

A Crack in Creation, Jennifer Doudna, Samuel Sternberg

If you haven’t heard of CRISPR before, chances are you’ll be hearing of it again pretty soon. It’s starting to be used in clinical trials to edit the genes of human embryos, and it’s already being used in countless research projects. It’s an amazing tool which could completely revolutionise gene editing, allowing very precise changes to be made with very little unintended impact. Doudna is one of the people who has been involved in developing CRISPR and recognising its potential, and her book covers exactly how it works and the potential it has — and some of the philosophical questions around how we’re going to use it.

The explanations of how CRISPR works are perfect: clear and precise, along with diagrams which help elucidate the processes described. Even if you already know a little about CRISPR, this account will probably help you understand just how it works and why it’s so revolutionary.

As far as the ethics/philosophy goes, Doudna says nothing particularly revolutionary. (It’s very much framed as her book, despite Sternberg’s involvement.) What struck me especially was her conviction that this is a decision that has to be made by people in general, not just scientists — it’s something I agree with very much, and why I have a science blog of my own.

An important read, I think — even if you’re not hugely into science/gene editing.

Rating: 5/5